Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
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| Định dạng: | Bài Báo |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1007/s12519-022-00645-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/6992 |
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oai:localhost:PNK-69922023-03-20T07:29:47Z Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins Guo-Liang, Xiao Yuan, Gao Hu, Hao ABCA3 proteins alveolar epithelial cells CC BY Surfactants produced by type II alveolar epithelial cells (AT2 cells) are usually present in inclusion organelles called lamellar bodies (LBs). The ATP-binding cassette subfamily A member 3 (ABCA3) transporter primarily exists in AT2 cells and is generally considered to be one of the critical regulators of biogenesis of LBs and surfactant metabolism in the lungs [1,2,3,4]. ABCA3 mutations are the most common cause of congenital surfactant dysfunction disorders (CSDDs), resulting in fatal neonatal respiratory distress and pediatric or adult interstitial lung disease [3, 5,6,7]. 2023-03-20T07:29:46Z 2023-03-20T07:29:46Z 2023 Article Book https://link.springer.com/article/10.1007/s12519-022-00645-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/6992 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
ABCA3 proteins alveolar epithelial cells |
| spellingShingle |
ABCA3 proteins alveolar epithelial cells Guo-Liang, Xiao Yuan, Gao Hu, Hao Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins |
| description |
CC BY |
| format |
Article |
| author |
Guo-Liang, Xiao Yuan, Gao Hu, Hao |
| author_facet |
Guo-Liang, Xiao Yuan, Gao Hu, Hao |
| author_sort |
Guo-Liang, Xiao |
| title |
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins |
| title_short |
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins |
| title_full |
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins |
| title_fullStr |
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins |
| title_full_unstemmed |
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins |
| title_sort |
novel insights into congenital surfactant dysfunction disorders by in silico analysis of abca3 proteins |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1007/s12519-022-00645-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/6992 |
| _version_ |
1760915945521414144 |
| score |
8.891145 |