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Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins

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Main Authors: Guo-Liang, Xiao, Yuan, Gao, Hu, Hao
Format: Article
Language:English
Published: Springer 2023
Subjects:
ABCA3 proteins
alveolar epithelial cells
Online Access:https://link.springer.com/article/10.1007/s12519-022-00645-y
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6992
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spelling oai:localhost:PNK-69922023-03-20T07:29:47Z Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins Guo-Liang, Xiao Yuan, Gao Hu, Hao ABCA3 proteins alveolar epithelial cells CC BY Surfactants produced by type II alveolar epithelial cells (AT2 cells) are usually present in inclusion organelles called lamellar bodies (LBs). The ATP-binding cassette subfamily A member 3 (ABCA3) transporter primarily exists in AT2 cells and is generally considered to be one of the critical regulators of biogenesis of LBs and surfactant metabolism in the lungs [1,2,3,4]. ABCA3 mutations are the most common cause of congenital surfactant dysfunction disorders (CSDDs), resulting in fatal neonatal respiratory distress and pediatric or adult interstitial lung disease [3, 5,6,7]. 2023-03-20T07:29:46Z 2023-03-20T07:29:46Z 2023 Article Book https://link.springer.com/article/10.1007/s12519-022-00645-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/6992 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic ABCA3 proteins
alveolar epithelial cells
spellingShingle ABCA3 proteins
alveolar epithelial cells
Guo-Liang, Xiao
Yuan, Gao
Hu, Hao
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
description CC BY
format Article
author Guo-Liang, Xiao
Yuan, Gao
Hu, Hao
author_facet Guo-Liang, Xiao
Yuan, Gao
Hu, Hao
author_sort Guo-Liang, Xiao
title Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
title_short Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
title_full Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
title_fullStr Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
title_full_unstemmed Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins
title_sort novel insights into congenital surfactant dysfunction disorders by in silico analysis of abca3 proteins
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1007/s12519-022-00645-y
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6992
_version_ 1760915945521414144
score 8.891145

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