The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
Cc-BY
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s11671-023-03900-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/9526 |
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oai:localhost:PNK-95262023-10-11T04:16:10Z The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus Ren, Caifeng Ke, Qiyun Fan, Xiaoxia S-Rhe/Ag and L-Rhe/Ag PRRSV Cc-BY Traditional Chinese medicines (TCMs)/nanopreparations as viral antagonists exhibited a structure–function correlation, i.e., the differences in surface area/volume ratio caused by the variations in shape and size could result in different biochemical properties and biological activities, suggesting an important impact of morphology and structure on the antiviral activity of TCM-based nanoparticles. However, few studies paid attention to this aspect. Here, the effect of TCM-based nanoparticles with different morphologies on their antiviral activity was explored by synthesizing rhein/silver nanocomposites (Rhe@AgNPs) with spherical (S-Rhe/Ag) and linear (L-Rhe/Ag) morphologies, using rhein (an active TCM ingredient) as a reducing agent and taking its self-assembly advantage. Using porcine reproductive and respiratory syndrome virus (PRRSV) as a model virus, the inhibitory effects of S-Rhe/Ag and L-Rhe/Ag on PRRSV were compared. Results showed that the product morphology could be regulated by varying pH values, and both S- and L-Rhe/Ag exhibited good dispersion and stability, but with a smaller size for L-Rhe/Ag. 2023-10-11T04:16:10Z 2023-10-11T04:16:10Z 2023 Book https://link.springer.com/article/10.1186/s11671-023-03900-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/9526 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
S-Rhe/Ag and L-Rhe/Ag PRRSV |
| spellingShingle |
S-Rhe/Ag and L-Rhe/Ag PRRSV Ren, Caifeng Ke, Qiyun Fan, Xiaoxia The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| description |
Cc-BY |
| format |
Book |
| author |
Ren, Caifeng Ke, Qiyun Fan, Xiaoxia |
| author_facet |
Ren, Caifeng Ke, Qiyun Fan, Xiaoxia |
| author_sort |
Ren, Caifeng |
| title |
The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| title_short |
The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| title_full |
The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| title_fullStr |
The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| title_full_unstemmed |
The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| title_sort |
shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s11671-023-03900-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/9526 |
| _version_ |
1779578920705720320 |
| score |
8.887836 |