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The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus

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Bibliographic Details
Main Authors: Ren, Caifeng, Ke, Qiyun, Fan, Xiaoxia
Format: Book
Language:English
Published: Springer 2023
Subjects:
S-Rhe/Ag and L-Rhe/Ag
PRRSV
Online Access:https://link.springer.com/article/10.1186/s11671-023-03900-x
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9526
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spelling oai:localhost:PNK-95262023-10-11T04:16:10Z The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus Ren, Caifeng Ke, Qiyun Fan, Xiaoxia S-Rhe/Ag and L-Rhe/Ag PRRSV Cc-BY Traditional Chinese medicines (TCMs)/nanopreparations as viral antagonists exhibited a structure–function correlation, i.e., the differences in surface area/volume ratio caused by the variations in shape and size could result in different biochemical properties and biological activities, suggesting an important impact of morphology and structure on the antiviral activity of TCM-based nanoparticles. However, few studies paid attention to this aspect. Here, the effect of TCM-based nanoparticles with different morphologies on their antiviral activity was explored by synthesizing rhein/silver nanocomposites (Rhe@AgNPs) with spherical (S-Rhe/Ag) and linear (L-Rhe/Ag) morphologies, using rhein (an active TCM ingredient) as a reducing agent and taking its self-assembly advantage. Using porcine reproductive and respiratory syndrome virus (PRRSV) as a model virus, the inhibitory effects of S-Rhe/Ag and L-Rhe/Ag on PRRSV were compared. Results showed that the product morphology could be regulated by varying pH values, and both S- and L-Rhe/Ag exhibited good dispersion and stability, but with a smaller size for L-Rhe/Ag. 2023-10-11T04:16:10Z 2023-10-11T04:16:10Z 2023 Book https://link.springer.com/article/10.1186/s11671-023-03900-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/9526 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic S-Rhe/Ag and L-Rhe/Ag
PRRSV
spellingShingle S-Rhe/Ag and L-Rhe/Ag
PRRSV
Ren, Caifeng
Ke, Qiyun
Fan, Xiaoxia
The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
description Cc-BY
format Book
author Ren, Caifeng
Ke, Qiyun
Fan, Xiaoxia
author_facet Ren, Caifeng
Ke, Qiyun
Fan, Xiaoxia
author_sort Ren, Caifeng
title The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
title_short The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
title_full The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
title_fullStr The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
title_full_unstemmed The shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
title_sort shape-dependent inhibitory effect of rhein/silver nanocomposites on porcine reproductive and respiratory syndrome virus
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s11671-023-03900-x
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9526
_version_ 1779578920705720320
score 8.887836

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