Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts
CC-BY
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s12645-023-00220-8 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8949 |
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oai:localhost:PNK-89492023-08-25T04:48:39Z Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts Kousar, Kousain Naseer, Faiza Abduh, Maisa S. NDV acid for CD44 CC-BY Newcastle disease virus (NDV) Lasota strain has proven oncolytic activity. One shortcoming associated with this treatment modality is the immune neutralization of the virus in body, mediated by natural killer cells and macrophages. This study aims at encapsulating the oncolytic virus in thiolated chitosan nanoparticles, surface functionalized with hyaluronic acid for CD44 targeted delivery and sustained release of NDV in cervical cancer tumors. These nanoparticles were tested for oncolytic potential in HeLa cells and cervical cancer xenograft model. 2023-08-25T04:48:39Z 2023-08-25T04:48:39Z 2023 Book https://link.springer.com/article/10.1186/s12645-023-00220-8 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8949 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
NDV acid for CD44 |
| spellingShingle |
NDV acid for CD44 Kousar, Kousain Naseer, Faiza Abduh, Maisa S. Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| description |
CC-BY |
| format |
Book |
| author |
Kousar, Kousain Naseer, Faiza Abduh, Maisa S. |
| author_facet |
Kousar, Kousain Naseer, Faiza Abduh, Maisa S. |
| author_sort |
Kousar, Kousain |
| title |
Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| title_short |
Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| title_full |
Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| title_fullStr |
Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| title_full_unstemmed |
Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| title_sort |
green synthesis of oncolytic newcastle disease virus-loaded thiolated chitosan nanoformulation for cd44 targeted delivery and sustained release of virus in cervical cancer xenografts |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s12645-023-00220-8 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8949 |
| _version_ |
1775230274603319296 |
| score |
8.891145 |