Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1007/s10237-023-01687-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8504 |
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oai:localhost:PNK-85042023-05-25T03:47:39Z Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models Alireza, Jafarinia Gian Marco, Melito Thomas Stephan, Müller TBAD FL CC BY Type B aortic dissection (TBAD) carries a high risk of complications, particularly with a partially thrombosed or patent false lumen (FL). Therefore, uncovering the risk factors leading to FL thrombosis is crucial to identify high-risk patients. Although studies have shown that morphological parameters of the dissected aorta are related to FL thrombosis, often conflicting results have been reported. We show that recent models of thrombus evolution in combination with sensitivity analysis methods can provide valuable insights into how combinations of morphological parameters affect the prospect of FL thrombosis. Based on clinical data, an idealized geometry of a TBAD is generated and parameterized. After implementing the thrombus model in computational fluid dynamics simulations, a global sensitivity analysis for selected morphological parameters is performed. We then introduce dimensionless morphological parameters to scale the results to individual patients. 2023-05-25T03:47:39Z 2023-05-25T03:47:39Z 2023 Book https://link.springer.com/article/10.1007/s10237-023-01687-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8504 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
TBAD FL |
| spellingShingle |
TBAD FL Alireza, Jafarinia Gian Marco, Melito Thomas Stephan, Müller Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models |
| description |
CC BY |
| format |
Book |
| author |
Alireza, Jafarinia Gian Marco, Melito Thomas Stephan, Müller |
| author_facet |
Alireza, Jafarinia Gian Marco, Melito Thomas Stephan, Müller |
| author_sort |
Alireza, Jafarinia |
| title |
Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models |
| title_short |
Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models |
| title_full |
Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models |
| title_fullStr |
Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models |
| title_full_unstemmed |
Morphological parameters affecting false lumen thrombosis following type B aortic dissection: a systematic study based on simulations of idealized models |
| title_sort |
morphological parameters affecting false lumen thrombosis following type b aortic dissection: a systematic study based on simulations of idealized models |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1007/s10237-023-01687-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8504 |
| _version_ |
1772331160520622080 |
| score |
8.891695 |