Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
CC BY
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1007/s11538-023-01142-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479 |
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oai:localhost:PNK-74792023-04-04T03:46:16Z Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development Ishraq U., Ahmed Helen M., Byrne Mary R., Myerscough Atherosclerosis formation of plaques CC BY Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment. These changes include higher death rates, defective efferocytic uptake of dead cells, and reduced rates of emigration. We develop a free boundary multiphase model for early atherosclerotic plaques, and we use it to investigate the effects of impaired macrophage anti-inflammatory behaviour on plaque structure and growth. 2023-04-04T03:46:16Z 2023-04-04T03:46:16Z 2023 Book https://link.springer.com/article/10.1007/s11538-023-01142-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
Atherosclerosis formation of plaques |
| spellingShingle |
Atherosclerosis formation of plaques Ishraq U., Ahmed Helen M., Byrne Mary R., Myerscough Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
| description |
CC BY |
| format |
Book |
| author |
Ishraq U., Ahmed Helen M., Byrne Mary R., Myerscough |
| author_facet |
Ishraq U., Ahmed Helen M., Byrne Mary R., Myerscough |
| author_sort |
Ishraq U., Ahmed |
| title |
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
| title_short |
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
| title_full |
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
| title_fullStr |
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
| title_full_unstemmed |
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
| title_sort |
macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1007/s11538-023-01142-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479 |
| _version_ |
1762274898386878464 |
| score |
8.891145 |