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Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development

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Bibliographic Details
Main Authors: Ishraq U., Ahmed, Helen M., Byrne, Mary R., Myerscough
Format: Book
Language:English
Published: Springer 2023
Subjects:
Atherosclerosis
formation of plaques
Online Access:https://link.springer.com/article/10.1007/s11538-023-01142-7
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479
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spelling oai:localhost:PNK-74792023-04-04T03:46:16Z Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development Ishraq U., Ahmed Helen M., Byrne Mary R., Myerscough Atherosclerosis formation of plaques CC BY Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment. These changes include higher death rates, defective efferocytic uptake of dead cells, and reduced rates of emigration. We develop a free boundary multiphase model for early atherosclerotic plaques, and we use it to investigate the effects of impaired macrophage anti-inflammatory behaviour on plaque structure and growth. 2023-04-04T03:46:16Z 2023-04-04T03:46:16Z 2023 Book https://link.springer.com/article/10.1007/s11538-023-01142-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic Atherosclerosis
formation of plaques
spellingShingle Atherosclerosis
formation of plaques
Ishraq U., Ahmed
Helen M., Byrne
Mary R., Myerscough
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
description CC BY
format Book
author Ishraq U., Ahmed
Helen M., Byrne
Mary R., Myerscough
author_facet Ishraq U., Ahmed
Helen M., Byrne
Mary R., Myerscough
author_sort Ishraq U., Ahmed
title Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
title_short Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
title_full Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
title_fullStr Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
title_full_unstemmed Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
title_sort macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1007/s11538-023-01142-7
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479
_version_ 1762274898386878464
score 8.891145

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