Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
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Định dạng: | Sách |
Ngôn ngữ: | English |
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Springer
2023
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Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s12890-023-02350-6 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7113 |
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oai:localhost:PNK-71132023-03-24T01:18:40Z Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes Guangyao, Wang Anqiao, Wang Li, Wang lung adenocarcinoma cuprotosis-related genes CC BY Cuprotosis is a novel and unique form of cell death that is of great value in a variety of cancers. However, the prognostic role of cuprotosis-related genes (CRGs) in lung cancer remains undetermined. We compared the expression profile of CRGs in lung adenocarcinoma (LUAD) patients, revealing the genetic alterations and inter-gene correlations of CRGs. Based on 13 CRGs, LUAD patients could be well differentiated into two molecular subgroups, and the differentially expressed genes (DEGs) in these molecular subtypes were identified. Furthermore, 10 cuprotosis pattern-related DEGs with a significant prognostic value were obtained for constructing a prognostic model. 2023-03-24T01:18:40Z 2023-03-24T01:18:40Z 2023 Book https://link.springer.com/article/10.1186/s12890-023-02350-6 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7113 en application/pdf Springer |
institution |
Digital Phenikaa |
collection |
Digital Phenikaa |
language |
English |
topic |
lung adenocarcinoma cuprotosis-related genes |
spellingShingle |
lung adenocarcinoma cuprotosis-related genes Guangyao, Wang Anqiao, Wang Li, Wang Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
description |
CC BY |
format |
Book |
author |
Guangyao, Wang Anqiao, Wang Li, Wang |
author_facet |
Guangyao, Wang Anqiao, Wang Li, Wang |
author_sort |
Guangyao, Wang |
title |
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
title_short |
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
title_full |
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
title_fullStr |
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
title_full_unstemmed |
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
title_sort |
identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes |
publisher |
Springer |
publishDate |
2023 |
url |
https://link.springer.com/article/10.1186/s12890-023-02350-6 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7113 |
_version_ |
1761278338526085120 |
score |
8.891053 |