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Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes

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Bibliographic Details
Main Authors: Guangyao, Wang, Anqiao, Wang, Li, Wang
Format: Book
Language:English
Published: Springer 2023
Subjects:
lung adenocarcinoma
cuprotosis-related genes
Online Access:https://link.springer.com/article/10.1186/s12890-023-02350-6
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7113
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spelling oai:localhost:PNK-71132023-03-24T01:18:40Z Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes Guangyao, Wang Anqiao, Wang Li, Wang lung adenocarcinoma cuprotosis-related genes CC BY Cuprotosis is a novel and unique form of cell death that is of great value in a variety of cancers. However, the prognostic role of cuprotosis-related genes (CRGs) in lung cancer remains undetermined. We compared the expression profile of CRGs in lung adenocarcinoma (LUAD) patients, revealing the genetic alterations and inter-gene correlations of CRGs. Based on 13 CRGs, LUAD patients could be well differentiated into two molecular subgroups, and the differentially expressed genes (DEGs) in these molecular subtypes were identified. Furthermore, 10 cuprotosis pattern-related DEGs with a significant prognostic value were obtained for constructing a prognostic model. 2023-03-24T01:18:40Z 2023-03-24T01:18:40Z 2023 Book https://link.springer.com/article/10.1186/s12890-023-02350-6 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7113 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic lung adenocarcinoma
cuprotosis-related genes
spellingShingle lung adenocarcinoma
cuprotosis-related genes
Guangyao, Wang
Anqiao, Wang
Li, Wang
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
description CC BY
format Book
author Guangyao, Wang
Anqiao, Wang
Li, Wang
author_facet Guangyao, Wang
Anqiao, Wang
Li, Wang
author_sort Guangyao, Wang
title Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
title_short Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
title_full Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
title_fullStr Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
title_full_unstemmed Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
title_sort identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s12890-023-02350-6
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7113
_version_ 1761278338526085120
score 8.887836

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