Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s13613-023-01105-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7010 |
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oai:localhost:PNK-70102023-03-21T02:40:11Z Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial Damien, Roux Nicolas, Benichou David, Hajage minimal inhibitory concentration acute kidney injury CC BY Sepsis prognosis correlates with antibiotic adequacy at the early phase. This adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic dosage. Optimal efficacy of beta-lactams mandates concentrations above the minimal inhibitory concentration (MIC) of the targeted bacteria for the longest time possible over the day. Septic acute kidney injury (AKI) is the most common AKI syndrome in ICU and often mandates renal replacement therapy (RRT) initiation. Both severe AKI and RRT may increase outside target antibiotic concentrations and ultimately alter patient’s prognosis. 2023-03-21T02:40:10Z 2023-03-21T02:40:10Z 2023 Book https://link.springer.com/article/10.1186/s13613-023-01105-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7010 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
minimal inhibitory concentration acute kidney injury |
| spellingShingle |
minimal inhibitory concentration acute kidney injury Damien, Roux Nicolas, Benichou David, Hajage Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial |
| description |
CC BY |
| format |
Book |
| author |
Damien, Roux Nicolas, Benichou David, Hajage |
| author_facet |
Damien, Roux Nicolas, Benichou David, Hajage |
| author_sort |
Damien, Roux |
| title |
Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial |
| title_short |
Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial |
| title_full |
Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial |
| title_fullStr |
Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial |
| title_full_unstemmed |
Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial |
| title_sort |
impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the betakiki study—an ancillary study of a randomized controlled trial |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s13613-023-01105-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7010 |
| _version_ |
1761006542948139008 |
| score |
8.891145 |