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Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial

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Bibliographic Details
Main Authors: Damien, Roux, Nicolas, Benichou, David, Hajage
Format: Book
Language:English
Published: Springer 2023
Subjects:
minimal inhibitory concentration
acute kidney injury
Online Access:https://link.springer.com/article/10.1186/s13613-023-01105-0
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7010
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spelling oai:localhost:PNK-70102023-03-21T02:40:11Z Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial Damien, Roux Nicolas, Benichou David, Hajage minimal inhibitory concentration acute kidney injury CC BY Sepsis prognosis correlates with antibiotic adequacy at the early phase. This adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic dosage. Optimal efficacy of beta-lactams mandates concentrations above the minimal inhibitory concentration (MIC) of the targeted bacteria for the longest time possible over the day. Septic acute kidney injury (AKI) is the most common AKI syndrome in ICU and often mandates renal replacement therapy (RRT) initiation. Both severe AKI and RRT may increase outside target antibiotic concentrations and ultimately alter patient’s prognosis. 2023-03-21T02:40:10Z 2023-03-21T02:40:10Z 2023 Book https://link.springer.com/article/10.1186/s13613-023-01105-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7010 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic minimal inhibitory concentration
acute kidney injury
spellingShingle minimal inhibitory concentration
acute kidney injury
Damien, Roux
Nicolas, Benichou
David, Hajage
Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
description CC BY
format Book
author Damien, Roux
Nicolas, Benichou
David, Hajage
author_facet Damien, Roux
Nicolas, Benichou
David, Hajage
author_sort Damien, Roux
title Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
title_short Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
title_full Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
title_fullStr Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
title_full_unstemmed Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
title_sort impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the betakiki study—an ancillary study of a randomized controlled trial
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s13613-023-01105-0
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7010
_version_ 1761006542948139008
score 8.891145

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