Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Chủ đề: | |
| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s13054-023-04382-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6995 |
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oai:localhost:PNK-69952023-03-20T08:24:56Z Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses Yupei, Li Yu, Chen Tinghang, Yang high mobility group box-1 damage-associated molecular patterns CC BY Both high mobility group box-1 (HMGB1) and histones are major damage-associated molecular patterns (DAPMs) that mediate lethal systemic inflammation, activation of the complement and coagulation system, endothelial injury and multiple organ dysfunction syndrome in critical illnesses. Although accumulating evidence collectively shows that targeting HMGB1 or histones by their specific antibodies or inhibitors could significantly mitigate aberrant immune responses in multiple critically ill animal models, routine clinical use of such agents is still not recommended by any guideline. 2023-03-20T08:24:56Z 2023-03-20T08:24:56Z 2023 Book https://link.springer.com/article/10.1186/s13054-023-04382-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6995 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
high mobility group box-1 damage-associated molecular patterns |
| spellingShingle |
high mobility group box-1 damage-associated molecular patterns Yupei, Li Yu, Chen Tinghang, Yang Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| description |
CC BY |
| format |
Book |
| author |
Yupei, Li Yu, Chen Tinghang, Yang |
| author_facet |
Yupei, Li Yu, Chen Tinghang, Yang |
| author_sort |
Yupei, Li |
| title |
Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| title_short |
Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| title_full |
Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| title_fullStr |
Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| title_full_unstemmed |
Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| title_sort |
targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s13054-023-04382-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6995 |
| _version_ |
1760915945952378880 |
| score |
8.891053 |