Bioengineered extracellular vesicles: future of precision medicine for sepsis

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Tác giả chính: Aina, Areny-Balagueró, Anna, Solé-Porta, Marta, Camprubí-Rimblas
Định dạng: Sách
Ngôn ngữ:English
Nhà xuất bản: Springer 2023
Chủ đề:
Truy cập trực tuyến:https://link.springer.com/article/10.1186/s40635-023-00491-w
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6929
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spelling oai:localhost:PNK-69292023-03-16T04:29:26Z Bioengineered extracellular vesicles: future of precision medicine for sepsis Aina, Areny-Balagueró Anna, Solé-Porta Marta, Camprubí-Rimblas future of precision medicine for sepsis versatility of extracellular vesicles CC BY Sepsis is a syndromic response to infection and is frequently a final common pathway to death from many infectious diseases worldwide. The complexity and high heterogeneity of sepsis hinder the possibility to treat all patients with the same protocol, requiring personalized management. The versatility of extracellular vesicles (EVs) and their contribution to sepsis progression bring along promises for one-to-one tailoring sepsis treatment and diagnosis. In this article, we critically review the endogenous role of EVs in sepsis progression and how current advancements have improved EVs-based therapies toward their translational future clinical application, with innovative strategies to enhance EVs effect. More complex approaches, including hybrid and fully synthetic nanocarriers that mimic EVs, are also discussed. Several pre-clinical and clinical studies are examined through the review to offer a general outlook of the current and future perspectives of EV-based sepsis diagnosis and treatment. 2023-03-16T04:29:26Z 2023-03-16T04:29:26Z 2023 Book https://link.springer.com/article/10.1186/s40635-023-00491-w https://dlib.phenikaa-uni.edu.vn/handle/PNK/6929 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic future of precision medicine for sepsis
versatility of extracellular vesicles
spellingShingle future of precision medicine for sepsis
versatility of extracellular vesicles
Aina, Areny-Balagueró
Anna, Solé-Porta
Marta, Camprubí-Rimblas
Bioengineered extracellular vesicles: future of precision medicine for sepsis
description CC BY
format Book
author Aina, Areny-Balagueró
Anna, Solé-Porta
Marta, Camprubí-Rimblas
author_facet Aina, Areny-Balagueró
Anna, Solé-Porta
Marta, Camprubí-Rimblas
author_sort Aina, Areny-Balagueró
title Bioengineered extracellular vesicles: future of precision medicine for sepsis
title_short Bioengineered extracellular vesicles: future of precision medicine for sepsis
title_full Bioengineered extracellular vesicles: future of precision medicine for sepsis
title_fullStr Bioengineered extracellular vesicles: future of precision medicine for sepsis
title_full_unstemmed Bioengineered extracellular vesicles: future of precision medicine for sepsis
title_sort bioengineered extracellular vesicles: future of precision medicine for sepsis
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s40635-023-00491-w
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6929
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