Bioengineered extracellular vesicles: future of precision medicine for sepsis
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2023
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Online Access: | https://link.springer.com/article/10.1186/s40635-023-00491-w https://dlib.phenikaa-uni.edu.vn/handle/PNK/6929 |
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oai:localhost:PNK-69292023-03-16T04:29:26Z Bioengineered extracellular vesicles: future of precision medicine for sepsis Aina, Areny-Balagueró Anna, Solé-Porta Marta, Camprubí-Rimblas future of precision medicine for sepsis versatility of extracellular vesicles CC BY Sepsis is a syndromic response to infection and is frequently a final common pathway to death from many infectious diseases worldwide. The complexity and high heterogeneity of sepsis hinder the possibility to treat all patients with the same protocol, requiring personalized management. The versatility of extracellular vesicles (EVs) and their contribution to sepsis progression bring along promises for one-to-one tailoring sepsis treatment and diagnosis. In this article, we critically review the endogenous role of EVs in sepsis progression and how current advancements have improved EVs-based therapies toward their translational future clinical application, with innovative strategies to enhance EVs effect. More complex approaches, including hybrid and fully synthetic nanocarriers that mimic EVs, are also discussed. Several pre-clinical and clinical studies are examined through the review to offer a general outlook of the current and future perspectives of EV-based sepsis diagnosis and treatment. 2023-03-16T04:29:26Z 2023-03-16T04:29:26Z 2023 Book https://link.springer.com/article/10.1186/s40635-023-00491-w https://dlib.phenikaa-uni.edu.vn/handle/PNK/6929 en application/pdf Springer |
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English |
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future of precision medicine for sepsis versatility of extracellular vesicles |
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future of precision medicine for sepsis versatility of extracellular vesicles Aina, Areny-Balagueró Anna, Solé-Porta Marta, Camprubí-Rimblas Bioengineered extracellular vesicles: future of precision medicine for sepsis |
description |
CC BY |
format |
Book |
author |
Aina, Areny-Balagueró Anna, Solé-Porta Marta, Camprubí-Rimblas |
author_facet |
Aina, Areny-Balagueró Anna, Solé-Porta Marta, Camprubí-Rimblas |
author_sort |
Aina, Areny-Balagueró |
title |
Bioengineered extracellular vesicles: future of precision medicine for sepsis |
title_short |
Bioengineered extracellular vesicles: future of precision medicine for sepsis |
title_full |
Bioengineered extracellular vesicles: future of precision medicine for sepsis |
title_fullStr |
Bioengineered extracellular vesicles: future of precision medicine for sepsis |
title_full_unstemmed |
Bioengineered extracellular vesicles: future of precision medicine for sepsis |
title_sort |
bioengineered extracellular vesicles: future of precision medicine for sepsis |
publisher |
Springer |
publishDate |
2023 |
url |
https://link.springer.com/article/10.1186/s40635-023-00491-w https://dlib.phenikaa-uni.edu.vn/handle/PNK/6929 |
_version_ |
1760553560046567424 |
score |
8.891145 |