Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6901 |
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oai:localhost:PNK-69012023-03-16T06:36:41Z Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin Postmenopausal osteoporosis bisphosphonates and parathyroid hormone CC BY Postmenopausal osteoporosis (PMOP) is a common bone disorder characterized by low bone mineral density and microstructure deterioration [1]. It is estimated that more than 15% of postmenopausal women over 50 years old are suffering in PMOP worldwide [2]. Most of them have low back pain, hunchback and fragility fractures in different degrees [3]. Although there exist a large amount of anti-osteoporosis drugs such as active vitamin D, estrogen receptor modulators, bisphosphonates and parathyroid hormone [4], various undesirable effects limit their application and efficacy [5]. Natural products and herbs attract increasing attention for their potential anti-osteoporosis effects and relative safety 2023-03-16T04:17:32Z 2023-03-16T04:17:32Z 2023 Book https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6901 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
Postmenopausal osteoporosis bisphosphonates and parathyroid hormone |
| spellingShingle |
Postmenopausal osteoporosis bisphosphonates and parathyroid hormone Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| description |
CC BY |
| format |
Book |
| author |
Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin |
| author_facet |
Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin |
| author_sort |
Chenjie, Xia |
| title |
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| title_short |
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| title_full |
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| title_fullStr |
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| title_full_unstemmed |
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| title_sort |
network pharmacology-based mechanism prediction and pharmacological validation of bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6901 |
| _version_ |
1760553557467070464 |
| score |
8.881002 |