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Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice

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Main Authors: Chenjie, Xia, Haowei, Zhu, Jin, Li, Hongting, Jin
Format: Book
Language:English
Published: Springer 2023
Subjects:
Postmenopausal osteoporosis
bisphosphonates and parathyroid hormone
Online Access:https://link.springer.com/article/10.1186/s13018-023-03696-7
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6901
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spelling oai:localhost:PNK-69012023-03-16T06:36:41Z Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin Postmenopausal osteoporosis bisphosphonates and parathyroid hormone CC BY Postmenopausal osteoporosis (PMOP) is a common bone disorder characterized by low bone mineral density and microstructure deterioration [1]. It is estimated that more than 15% of postmenopausal women over 50 years old are suffering in PMOP worldwide [2]. Most of them have low back pain, hunchback and fragility fractures in different degrees [3]. Although there exist a large amount of anti-osteoporosis drugs such as active vitamin D, estrogen receptor modulators, bisphosphonates and parathyroid hormone [4], various undesirable effects limit their application and efficacy [5]. Natural products and herbs attract increasing attention for their potential anti-osteoporosis effects and relative safety 2023-03-16T04:17:32Z 2023-03-16T04:17:32Z 2023 Book https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6901 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic Postmenopausal osteoporosis
bisphosphonates and parathyroid hormone
spellingShingle Postmenopausal osteoporosis
bisphosphonates and parathyroid hormone
Chenjie, Xia
Haowei, Zhu
Jin, Li
Hongting, Jin
Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
description CC BY
format Book
author Chenjie, Xia
Haowei, Zhu
Jin, Li
Hongting, Jin
author_facet Chenjie, Xia
Haowei, Zhu
Jin, Li
Hongting, Jin
author_sort Chenjie, Xia
title Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_short Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_full Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_fullStr Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_full_unstemmed Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_sort network pharmacology-based mechanism prediction and pharmacological validation of bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s13018-023-03696-7
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6901
_version_ 1760553557467070464
score 8.881002

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