Staff View: Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice

Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice

Postmenopausal osteoporosis (PMOP) is a common bone disorder characterized by low bone mineral density and microstructure deterioration [1]. It is estimated that more than 15% of postmenopausal women over 50 years old are suffering in PMOP worldwide [2]. Most of them have low back pain, hunchback an...

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Main Authors:	Chenjie, Xia, Haowei, Zhu, Jin, Li, Hongting, Jin
Format:	Book
Language:	English
Published:	Springer 2023
Subjects:	Postmenopausal osteoporosis bisphosphonates and parathyroid hormone
Online Access:	https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6765
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spelling	oai:localhost:PNK-67652023-03-14T09:07:14Z Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin Postmenopausal osteoporosis bisphosphonates and parathyroid hormone Postmenopausal osteoporosis (PMOP) is a common bone disorder characterized by low bone mineral density and microstructure deterioration [1]. It is estimated that more than 15% of postmenopausal women over 50 years old are suffering in PMOP worldwide [2]. Most of them have low back pain, hunchback and fragility fractures in different degrees [3]. Although there exist a large amount of anti-osteoporosis drugs such as active vitamin D, estrogen receptor modulators, bisphosphonates and parathyroid hormone [4], various undesirable effects limit their application and efficacy [5]. Natural products and herbs attract increasing attention for their potential anti-osteoporosis effects and relative safety 2023-03-14T08:34:06Z 2023-03-14T08:34:06Z 2023 Book https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6765 en application/pdf Springer
institution	Digital Phenikaa
collection	Digital Phenikaa
language	English
topic	Postmenopausal osteoporosis bisphosphonates and parathyroid hormone
spellingShingle	Postmenopausal osteoporosis bisphosphonates and parathyroid hormone Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
description	Postmenopausal osteoporosis (PMOP) is a common bone disorder characterized by low bone mineral density and microstructure deterioration [1]. It is estimated that more than 15% of postmenopausal women over 50 years old are suffering in PMOP worldwide [2]. Most of them have low back pain, hunchback and fragility fractures in different degrees [3]. Although there exist a large amount of anti-osteoporosis drugs such as active vitamin D, estrogen receptor modulators, bisphosphonates and parathyroid hormone [4], various undesirable effects limit their application and efficacy [5]. Natural products and herbs attract increasing attention for their potential anti-osteoporosis effects and relative safety
format	Book
author	Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin
author_facet	Chenjie, Xia Haowei, Zhu Jin, Li Hongting, Jin
author_sort	Chenjie, Xia
title	Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_short	Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_full	Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_fullStr	Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_full_unstemmed	Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
title_sort	network pharmacology-based mechanism prediction and pharmacological validation of bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
publisher	Springer
publishDate	2023
url	https://link.springer.com/article/10.1186/s13018-023-03696-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6765
_version_	1760372366144176128
score	8.887836

Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice

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