Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy de...
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John Wiley & Sons
2022
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Online Access: | https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5861 https://doi.org/10.1002/pssr.202100496 |
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oai:localhost:PNK-58612022-08-17T05:54:53Z Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons Anh D. Phan Nguyen K. Ngan Do T. Nga Nam B. Le Chu Viet Ha Photothermal Tailoring Drug A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy depends on optical properties of graphene plasmons, which are sensitive to structural parameters, and concentration of plasmonic nanostructures. By using theoretical modelling, temperature gradients of the bulk drug with different concentrations of graphene plasmons are calculated. From these, the temperature dependence of structural molecular relaxation and diffusion of indomethacin are determined and how the heating process significantly enhances the drug mobility is found out. 2022-07-13T01:59:44Z 2022-07-13T01:59:44Z 2022 Bài trích https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5861 https://doi.org/10.1002/pssr.202100496 en John Wiley & Sons |
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Photothermal Tailoring Drug |
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Photothermal Tailoring Drug Anh D. Phan Nguyen K. Ngan Do T. Nga Nam B. Le Chu Viet Ha Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
description |
A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy depends on optical properties of graphene plasmons, which are sensitive to structural parameters, and concentration of plasmonic nanostructures. By using theoretical modelling, temperature gradients of the bulk drug with different concentrations of graphene plasmons are calculated. From these, the temperature dependence of structural molecular relaxation and diffusion of indomethacin are determined and how the heating process significantly enhances the drug mobility is found out. |
format |
Bài trích |
author |
Anh D. Phan Nguyen K. Ngan Do T. Nga Nam B. Le Chu Viet Ha |
author_facet |
Anh D. Phan Nguyen K. Ngan Do T. Nga Nam B. Le Chu Viet Ha |
author_sort |
Anh D. Phan |
title |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_short |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_full |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_fullStr |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_full_unstemmed |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_sort |
tailoring drug mobility by photothermal heating of graphene plasmons |
publisher |
John Wiley & Sons |
publishDate |
2022 |
url |
https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5861 https://doi.org/10.1002/pssr.202100496 |
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1751856284391440384 |
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8.891145 |