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Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons

A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy de...

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Bibliographic Details
Main Authors: Anh D. Phan, Nguyen K. Ngan, Do T. Nga, Nam B. Le, Chu Viet Ha
Format: Bài trích
Language:English
Published: John Wiley & Sons 2022
Subjects:
Photothermal
Tailoring Drug
Online Access:https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5861
https://doi.org/10.1002/pssr.202100496
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spelling oai:localhost:PNK-58612022-08-17T05:54:53Z Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons Anh D. Phan Nguyen K. Ngan Do T. Nga Nam B. Le Chu Viet Ha Photothermal Tailoring Drug A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy depends on optical properties of graphene plasmons, which are sensitive to structural parameters, and concentration of plasmonic nanostructures. By using theoretical modelling, temperature gradients of the bulk drug with different concentrations of graphene plasmons are calculated. From these, the temperature dependence of structural molecular relaxation and diffusion of indomethacin are determined and how the heating process significantly enhances the drug mobility is found out. 2022-07-13T01:59:44Z 2022-07-13T01:59:44Z 2022 Bài trích https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5861 https://doi.org/10.1002/pssr.202100496 en John Wiley & Sons
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic Photothermal
Tailoring Drug
spellingShingle Photothermal
Tailoring Drug
Anh D. Phan
Nguyen K. Ngan
Do T. Nga
Nam B. Le
Chu Viet Ha
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
description A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy depends on optical properties of graphene plasmons, which are sensitive to structural parameters, and concentration of plasmonic nanostructures. By using theoretical modelling, temperature gradients of the bulk drug with different concentrations of graphene plasmons are calculated. From these, the temperature dependence of structural molecular relaxation and diffusion of indomethacin are determined and how the heating process significantly enhances the drug mobility is found out.
format Bài trích
author Anh D. Phan
Nguyen K. Ngan
Do T. Nga
Nam B. Le
Chu Viet Ha
author_facet Anh D. Phan
Nguyen K. Ngan
Do T. Nga
Nam B. Le
Chu Viet Ha
author_sort Anh D. Phan
title Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
title_short Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
title_full Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
title_fullStr Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
title_full_unstemmed Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
title_sort tailoring drug mobility by photothermal heating of graphene plasmons
publisher John Wiley & Sons
publishDate 2022
url https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5861
https://doi.org/10.1002/pssr.202100496
_version_ 1751856284391440384
score 8.891053

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