Stabilization of Single Turn Polyproline II Helices via Macrocyclic Hydrocarbon Staples
Polyproline II helix (PPII) is one of the secondary structures in proteins that play an important role in various biological processes. In this study, we have developed a new macrocyclization strategy that efficiently reinforces a model tetrapeptide into a PPII structure. We also elucidated some rel...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
ACS Publications
2020
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| Subjects: | |
| Online Access: | https://pubs.acs.org/doi/10.1021/acs.orglett.0c02914 https://dlib.phenikaa-uni.edu.vn/handle/PNK/586 https://doi.org/10.1021/acs.orglett.0c02914 |
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