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Adenovirus-α-Defensin Complexes Induce NLRP3-Associated Maturation of Human Phagocytes via Toll-Like Receptor 4 Engagement

Intramuscular delivery of human adenovirus (HAdV)-based vaccines leads to rapid recruitment of neutrophils, which then release antimicrobial peptides/proteins (AMPs). How these AMPs influence vaccine efficacy over the subsequent 24 h is poorly understood. In this study, we asked if human neutrophil...

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Bibliographic Details
Main Authors: Karsten, Eichholz, Tuan, Hiep Tran, Coraline ,Chéneau, Tran, Thi Thu Phuong, Océane, Paris, Martine, Pugniere, Eric, J. Kremer
Format: Bài trích
Language:English
Published: American Society for Microbiology 2022
Subjects:
Adenovirus-α-Defensin
NLRP3-Associated
Online Access:https://journals.asm.org/doi/10.1128/jvi.01850-21
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5735
https://doi.org/10.1128/jvi.01850-21
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https://journals.asm.org/doi/10.1128/jvi.01850-21
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5735
https://doi.org/10.1128/jvi.01850-21

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