Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3- yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents
Herein, we have designed and synthesized a series of the novel (E)-N'-((1-(4-chlorobenzyl)- 1H-indol-3-yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides (5) as potent small molecules activating procaspase- 3. The compounds were designed by the amalgamation of structural features of PAC-...
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| Main Authors: | , , , , |
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| Format: | Bài trích |
| Language: | English |
| Published: |
Bentham Science Publishers
2022
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| Subjects: | |
| Online Access: | https://www.eurekaselect.com/article/120263 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5726 http://dx.doi.org/10.2174/1871520622666220118154914 |
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