“A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433.
Danshen (Salvia miltiorrhiza) is a one of the most well-known medicinal herbs in the Oriental medicine for treatment of certain cardiovascular disoders. Our current research on triterpenoid component in danshen roots led to the isolation of a new highly hydroxylated ursane-type triterpene, urs-12,20...
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ACG Publications
2020
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| Truy cập trực tuyến: | https://dlib.phenikaa-uni.edu.vn/handle/PNK/243 https://doi.org/10.25135/rnp.97.18.07.330 |
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oai:localhost:PNK-2432022-08-17T05:54:41Z “A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. Nguyen Huu Tung Le Quoc Hung Phuong Thien Thuong Danshen (Salvia miltiorrhiza) is a one of the most well-known medicinal herbs in the Oriental medicine for treatment of certain cardiovascular disoders. Our current research on triterpenoid component in danshen roots led to the isolation of a new highly hydroxylated ursane-type triterpene, urs-12,20(30)-dien-3β,7β,24-triol-28-oic acid (2) and one known triterpene, epiasiatic acid (1). Their structures were elucidated on the basis of extensive spectroscopic analyses including NMR and MS spectra and comparison with literature data. The new compound 2 showed medium activity against HL-60 cells with the IC50 value of 16.3 μM. The obtained results of unique bioactive triterpenes from danshen contributed not only to its phytochemical profile associated with chemotaxanomy but also to biological evidence of the title plant. 2020-04-29T07:52:23Z 2020-04-29T07:52:23Z 2018 bccb00177 https://dlib.phenikaa-uni.edu.vn/handle/PNK/243 https://doi.org/10.25135/rnp.97.18.07.330 application/pdf ACG Publications |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| description |
Danshen (Salvia miltiorrhiza) is a one of the most well-known medicinal herbs in the Oriental medicine for treatment of certain cardiovascular disoders. Our current research on triterpenoid component in danshen roots led to the isolation of a new highly hydroxylated ursane-type triterpene, urs-12,20(30)-dien-3β,7β,24-triol-28-oic acid (2) and one known triterpene, epiasiatic acid (1). Their structures were elucidated on the basis of extensive spectroscopic analyses including NMR and MS spectra and comparison with literature data. The new compound 2 showed medium activity against HL-60 cells with the IC50 value of 16.3 μM. The obtained results of unique bioactive triterpenes from danshen contributed not only to its phytochemical profile associated with chemotaxanomy but also to biological evidence of the title plant. |
| author2 |
Le Quoc Hung |
| author_facet |
Le Quoc Hung Nguyen Huu Tung |
| author |
Nguyen Huu Tung |
| spellingShingle |
Nguyen Huu Tung “A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. |
| author_sort |
Nguyen Huu Tung |
| title |
“A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. |
| title_short |
“A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. |
| title_full |
“A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. |
| title_fullStr |
“A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. |
| title_full_unstemmed |
“A new ursane-type triterpene from the danshen roots (Salvia miltiorrhiza Bunge)”. Records of Natural Products, 13 (2019) 429-433. |
| title_sort |
“a new ursane-type triterpene from the danshen roots (salvia miltiorrhiza bunge)”. records of natural products, 13 (2019) 429-433. |
| publisher |
ACG Publications |
| publishDate |
2020 |
| url |
https://dlib.phenikaa-uni.edu.vn/handle/PNK/243 https://doi.org/10.25135/rnp.97.18.07.330 |
| _version_ |
1751856300361252864 |
| score |
8.881002 |