Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s12645-023-00229-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508 |
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oai:localhost:PNK-95082023-10-09T03:36:37Z Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo Salim, Elsayed I. Mahfouz, Magdy E. Eltonouby, Eman A. BPE BPENP CC-BY Bee pollen extract (BPE)-based polymer nanoparticles (BPENP) were fabricated using bovine serum albumin (BSA) and targeted with folic acid and were further characterized. Mice groups are: Group 1 received saline, whereas Groups 2, 3, 4, 5, and 6 received a single dose of urethane, followed by weekly injections of butylated hydroxy-toluene (BHT). After the BHT injection, the mice in Groups 3, 4, 5, and 6 received BPE, Avastin, BPENP, and BPENP + Avastin, respectively. The number and size of tumors were decreased in Group 6 compared to those in the other groups. The ratios of early and late apoptotic cells in Groups 3, 4, 5, and 6 (42.8%, 41.4%, 26.2%, and 45.4%, respectively) were higher than that in the untreated group. The PCNA-labeling indexes (LI)% in tissues and lesions from Group 6 were lower than those in the other groups; on the other hand, the Caspase-3 LI (%) was higher than those in the other groups. 2023-10-09T03:36:37Z 2023-10-09T03:36:37Z 2023 Book https://link.springer.com/article/10.1186/s12645-023-00229-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
BPE BPENP |
| spellingShingle |
BPE BPENP Salim, Elsayed I. Mahfouz, Magdy E. Eltonouby, Eman A. Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| description |
CC-BY |
| format |
Book |
| author |
Salim, Elsayed I. Mahfouz, Magdy E. Eltonouby, Eman A. |
| author_facet |
Salim, Elsayed I. Mahfouz, Magdy E. Eltonouby, Eman A. |
| author_sort |
Salim, Elsayed I. |
| title |
Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| title_short |
Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| title_full |
Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| title_fullStr |
Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| title_full_unstemmed |
Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| title_sort |
based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s12645-023-00229-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508 |
| _version_ |
1779397739112562688 |
| score |
8.8926115 |