Cover Image

Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo

CC-BY

Saved in:
Bibliographic Details
Main Authors: Salim, Elsayed I., Mahfouz, Magdy E., Eltonouby, Eman A.
Format: Book
Language:English
Published: Springer 2023
Subjects:
BPE
BPENP
Online Access:https://link.springer.com/article/10.1186/s12645-023-00229-z
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:localhost:PNK-9508
record_format dspace
spelling oai:localhost:PNK-95082023-10-09T03:36:37Z Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo Salim, Elsayed I. Mahfouz, Magdy E. Eltonouby, Eman A. BPE BPENP CC-BY Bee pollen extract (BPE)-based polymer nanoparticles (BPENP) were fabricated using bovine serum albumin (BSA) and targeted with folic acid and were further characterized. Mice groups are: Group 1 received saline, whereas Groups 2, 3, 4, 5, and 6 received a single dose of urethane, followed by weekly injections of butylated hydroxy-toluene (BHT). After the BHT injection, the mice in Groups 3, 4, 5, and 6 received BPE, Avastin, BPENP, and BPENP + Avastin, respectively. The number and size of tumors were decreased in Group 6 compared to those in the other groups. The ratios of early and late apoptotic cells in Groups 3, 4, 5, and 6 (42.8%, 41.4%, 26.2%, and 45.4%, respectively) were higher than that in the untreated group. The PCNA-labeling indexes (LI)% in tissues and lesions from Group 6 were lower than those in the other groups; on the other hand, the Caspase-3 LI (%) was higher than those in the other groups. 2023-10-09T03:36:37Z 2023-10-09T03:36:37Z 2023 Book https://link.springer.com/article/10.1186/s12645-023-00229-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic BPE
BPENP
spellingShingle BPE
BPENP
Salim, Elsayed I.
Mahfouz, Magdy E.
Eltonouby, Eman A.
Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
description CC-BY
format Book
author Salim, Elsayed I.
Mahfouz, Magdy E.
Eltonouby, Eman A.
author_facet Salim, Elsayed I.
Mahfouz, Magdy E.
Eltonouby, Eman A.
author_sort Salim, Elsayed I.
title Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
title_short Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
title_full Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
title_fullStr Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
title_full_unstemmed Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
title_sort based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s12645-023-00229-z
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508
_version_ 1779397739112562688
score 8.881002

Similar Items