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Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans

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Bibliographic Details
Main Authors: Wei, Yunyun, Qiu, Jianfeng, Han, Ziqiang
Format: Book
Language:English
Published: Springer 2023
Subjects:
ICU patients
S. boulardii via encapsulating
Online Access:https://link.springer.com/article/10.1186/s40824-023-00443-1
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9484
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spelling oai:localhost:PNK-94842023-10-06T02:36:57Z Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans Wei, Yunyun Qiu, Jianfeng Han, Ziqiang ICU patients S. boulardii via encapsulating CC-BY For some ICU patients, an artificial airway must be established with an endotracheal tube, but Candida albicans can easily adhere to the tube surface and form a biofilm, leading to potentially life threatening fungal infections. Therefore, it is urgent to prevent and reduce C. albicans infections introduced by the endotracheal tube. However, there are few antifungal drugs effective against C. albicans, and each of these drugs may have adverse effects on human cells. Saccharomyces boulardii is regarded as an alternative strategy to inhibit the adhesion of C. albicans, but it is affected by environmental stress. We hypothesized that it is feasible to strengthen the antagonistic ability of S. boulardii via encapsulating and genetically modification. 2023-10-06T02:36:57Z 2023-10-06T02:36:57Z 2023 Book https://link.springer.com/article/10.1186/s40824-023-00443-1 https://dlib.phenikaa-uni.edu.vn/handle/PNK/9484 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic ICU patients
S. boulardii via encapsulating
spellingShingle ICU patients
S. boulardii via encapsulating
Wei, Yunyun
Qiu, Jianfeng
Han, Ziqiang
Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
description CC-BY
format Book
author Wei, Yunyun
Qiu, Jianfeng
Han, Ziqiang
author_facet Wei, Yunyun
Qiu, Jianfeng
Han, Ziqiang
author_sort Wei, Yunyun
title Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
title_short Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
title_full Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
title_fullStr Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
title_full_unstemmed Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a “house” to antagonize Candida albicans
title_sort antifungal bio-coating of endotracheal tube built by overexpressing the mcp1 gene of saccharomyces boulardii and employing hydrogel as a “house” to antagonize candida albicans
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s40824-023-00443-1
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9484
_version_ 1779307185863393280
score 8.881002

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