Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages

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Main Authors: Nascimento, Camila Sales, Tavares, Naiara Clemente, Batista, Izabella Cristina Andrade
Format: Book
Language:English
Published: Springer 2023
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Online Access:https://link.springer.com/article/10.1186/s12645-023-00225-3
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9035
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spelling oai:localhost:PNK-90352023-09-15T03:15:36Z Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages Nascimento, Camila Sales Tavares, Naiara Clemente Batista, Izabella Cristina Andrade Pani/y-Fe2O3) M2 macrophages CC-BY Breast cancer is the neoplastic disease with the highest incidence and mortality in the female population worldwide. Treatment remains challenging due to various factors. Therefore, it is of great importance to develop new therapeutic strategies that promote the safe destruction of neoplastic cells without compromising patients' quality of life. Among advances in the treatment of breast cancer, immunotherapy stands out as a promising trend. Recent studies have demonstrated the potential of iron oxide nanoparticles in promoting the reprogramming of M2 macrophages (pro-tumor phenotype) into M1 macrophages (anti-tumor phenotype) within the tumor microenvironment, resulting in potent antitumor effects. In this study, the effect of polyaniline-coated iron oxide nanoparticles (Pani/y-Fe2O3) on macrophage polarization and breast cancer cell death was investigated. 2023-09-15T03:15:35Z 2023-09-15T03:15:35Z 2023 Book https://link.springer.com/article/10.1186/s12645-023-00225-3 https://dlib.phenikaa-uni.edu.vn/handle/PNK/9035 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic Pani/y-Fe2O3)
M2 macrophages
spellingShingle Pani/y-Fe2O3)
M2 macrophages
Nascimento, Camila Sales
Tavares, Naiara Clemente
Batista, Izabella Cristina Andrade
Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
description CC-BY
format Book
author Nascimento, Camila Sales
Tavares, Naiara Clemente
Batista, Izabella Cristina Andrade
author_facet Nascimento, Camila Sales
Tavares, Naiara Clemente
Batista, Izabella Cristina Andrade
author_sort Nascimento, Camila Sales
title Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
title_short Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
title_full Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
title_fullStr Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
title_full_unstemmed Iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
title_sort iron oxide polyaniline-coated nanoparticles modulate tumor microenvironment in breast cancer: an in vitro study on the reprogramming of tumor-associated macrophages
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s12645-023-00225-3
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9035
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