In vitro and in vivo toxicity of carbon dots with different chemical compositions
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oai:localhost:PNK-90272023-09-15T02:05:15Z In vitro and in vivo toxicity of carbon dots with different chemical compositions Kuznietsova, Halyna Géloën, Alain Dziubenko, Nataliia CD_3011 CDF19 CC-BY Carbon dots (CDs) are easy-obtained nanoparticles with wide range of biological activity; however, their toxicity after prolonged exposure is poorly investigated. So, in vitro and in vivo toxicity of CDs with the surfaces enriched with hydroxylated hydrocarbon chains and methylene groups (CD_GE), carboxyl and phenol groups accompanied with nitrogen (CD_3011), trifluoromethyl (CDF19) or toluidine and aniline groups (CDN19) were aimed to be discovered. CDs’ in vitro toxicity was assessed on A549 cells (real-time cell analysis of impedance, fluorescence microscopy) after 24 h of incubation, and we observed no changes in cell viability and morphology. CDs’ in vivo toxicity was assessed on C57Bl6 mice after multiple dosages (5 mg/kg subcutaneously) for 14 days. 2023-09-15T02:05:15Z 2023-09-15T02:05:15Z 2023 Book https://link.springer.com/article/10.1186/s11671-023-03891-9 https://dlib.phenikaa-uni.edu.vn/handle/PNK/9027 en application/pdf Springer |
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CD_3011 CDF19 Kuznietsova, Halyna Géloën, Alain Dziubenko, Nataliia In vitro and in vivo toxicity of carbon dots with different chemical compositions |
description |
CC-BY |
format |
Book |
author |
Kuznietsova, Halyna Géloën, Alain Dziubenko, Nataliia |
author_facet |
Kuznietsova, Halyna Géloën, Alain Dziubenko, Nataliia |
author_sort |
Kuznietsova, Halyna |
title |
In vitro and in vivo toxicity of carbon dots with different chemical compositions |
title_short |
In vitro and in vivo toxicity of carbon dots with different chemical compositions |
title_full |
In vitro and in vivo toxicity of carbon dots with different chemical compositions |
title_fullStr |
In vitro and in vivo toxicity of carbon dots with different chemical compositions |
title_full_unstemmed |
In vitro and in vivo toxicity of carbon dots with different chemical compositions |
title_sort |
in vitro and in vivo toxicity of carbon dots with different chemical compositions |
publisher |
Springer |
publishDate |
2023 |
url |
https://link.springer.com/article/10.1186/s11671-023-03891-9 https://dlib.phenikaa-uni.edu.vn/handle/PNK/9027 |
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1779307147898650624 |
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8.891787 |