In vitro and in vivo toxicity of carbon dots with different chemical compositions

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Main Authors: Kuznietsova, Halyna, Géloën, Alain, Dziubenko, Nataliia
Format: Book
Language:English
Published: Springer 2023
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Online Access:https://link.springer.com/article/10.1186/s11671-023-03891-9
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9027
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spelling oai:localhost:PNK-90272023-09-15T02:05:15Z In vitro and in vivo toxicity of carbon dots with different chemical compositions Kuznietsova, Halyna Géloën, Alain Dziubenko, Nataliia CD_3011 CDF19 CC-BY Carbon dots (CDs) are easy-obtained nanoparticles with wide range of biological activity; however, their toxicity after prolonged exposure is poorly investigated. So, in vitro and in vivo toxicity of CDs with the surfaces enriched with hydroxylated hydrocarbon chains and methylene groups (CD_GE), carboxyl and phenol groups accompanied with nitrogen (CD_3011), trifluoromethyl (CDF19) or toluidine and aniline groups (CDN19) were aimed to be discovered. CDs’ in vitro toxicity was assessed on A549 cells (real-time cell analysis of impedance, fluorescence microscopy) after 24 h of incubation, and we observed no changes in cell viability and morphology. CDs’ in vivo toxicity was assessed on C57Bl6 mice after multiple dosages (5 mg/kg subcutaneously) for 14 days. 2023-09-15T02:05:15Z 2023-09-15T02:05:15Z 2023 Book https://link.springer.com/article/10.1186/s11671-023-03891-9 https://dlib.phenikaa-uni.edu.vn/handle/PNK/9027 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic CD_3011
CDF19
spellingShingle CD_3011
CDF19
Kuznietsova, Halyna
Géloën, Alain
Dziubenko, Nataliia
In vitro and in vivo toxicity of carbon dots with different chemical compositions
description CC-BY
format Book
author Kuznietsova, Halyna
Géloën, Alain
Dziubenko, Nataliia
author_facet Kuznietsova, Halyna
Géloën, Alain
Dziubenko, Nataliia
author_sort Kuznietsova, Halyna
title In vitro and in vivo toxicity of carbon dots with different chemical compositions
title_short In vitro and in vivo toxicity of carbon dots with different chemical compositions
title_full In vitro and in vivo toxicity of carbon dots with different chemical compositions
title_fullStr In vitro and in vivo toxicity of carbon dots with different chemical compositions
title_full_unstemmed In vitro and in vivo toxicity of carbon dots with different chemical compositions
title_sort in vitro and in vivo toxicity of carbon dots with different chemical compositions
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s11671-023-03891-9
https://dlib.phenikaa-uni.edu.vn/handle/PNK/9027
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score 8.881002