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Tissue-growth-based synthetic tree generation and perfusion simulation

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Bibliographic Details
Main Authors: Hyun Jin, Kim, Hans Christian, Rundfeldt, Inpyo, Lee
Format: Book
Language:English
Published: Springer 2023
Subjects:
perfusion simulation
Tissue-growth-based synthetic
Online Access:https://link.springer.com/article/10.1007/s10237-023-01703-8
https://dlib.phenikaa-uni.edu.vn/handle/PNK/8503
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spelling oai:localhost:PNK-85032023-05-25T03:44:54Z Tissue-growth-based synthetic tree generation and perfusion simulation Hyun Jin, Kim Hans Christian, Rundfeldt Inpyo, Lee perfusion simulation Tissue-growth-based synthetic CC BY Biological tissues receive oxygen and nutrients from blood vessels by developing an indispensable supply and demand relationship with the blood vessels. We implemented a synthetic tree generation algorithm by considering the interactions between the tissues and blood vessels. We first segment major arteries using medical image data and synthetic trees are generated originating from these segmented arteries. They grow into extensive networks of small vessels to fill the supplied tissues and satisfy the metabolic demand of them. Further, the algorithm is optimized to be executed in parallel without affecting the generated tree volumes. The generated vascular trees are used to simulate blood perfusion in the tissues by performing multiscale blood flow simulations. One-dimensional blood flow equations were used to solve for blood flow and pressure in the generated vascular trees and Darcy flow equations were solved for blood perfusion in the tissues using a porous model assumption. Both equations are coupled at terminal segments explicitly. 2023-05-25T03:44:54Z 2023-05-25T03:44:54Z 2023 Book https://link.springer.com/article/10.1007/s10237-023-01703-8 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8503 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic perfusion simulation
Tissue-growth-based synthetic
spellingShingle perfusion simulation
Tissue-growth-based synthetic
Hyun Jin, Kim
Hans Christian, Rundfeldt
Inpyo, Lee
Tissue-growth-based synthetic tree generation and perfusion simulation
description CC BY
format Book
author Hyun Jin, Kim
Hans Christian, Rundfeldt
Inpyo, Lee
author_facet Hyun Jin, Kim
Hans Christian, Rundfeldt
Inpyo, Lee
author_sort Hyun Jin, Kim
title Tissue-growth-based synthetic tree generation and perfusion simulation
title_short Tissue-growth-based synthetic tree generation and perfusion simulation
title_full Tissue-growth-based synthetic tree generation and perfusion simulation
title_fullStr Tissue-growth-based synthetic tree generation and perfusion simulation
title_full_unstemmed Tissue-growth-based synthetic tree generation and perfusion simulation
title_sort tissue-growth-based synthetic tree generation and perfusion simulation
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1007/s10237-023-01703-8
https://dlib.phenikaa-uni.edu.vn/handle/PNK/8503
_version_ 1772331160424153088
score 8.889492

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