Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study
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Springer
2023
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| Online Access: | https://link.springer.com/article/10.1186/s13065-023-00952-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/8189 |
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oai:localhost:PNK-81892023-04-21T02:54:20Z Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study Ahmed Faried Abdel, Hakiem Ahmed Mohsen Kamal, El-Sagheir Mohammed E., Draz sperm DNA of two antiviral agents CC BY The direct binding of antiviral agents; Daclatasvir and valacyclovir and green synthesized nanoparticles to salmon sperm DNA have been assessed in a comparative study. The nanoparticles were synthesized by the hydrothermal autoclave method and have been fully characterized. The interactive behavior and competitive binding of the analytes to DNA in addition to the thermodynamic properties were deeply investigated by the UV–visible spectroscopy. The binding constants were monitored in the physiological pH conditions to be 1.65 × 106, 4.92 × 105 and 3.12 × 105 for daclatasvir,valacyclovir and quantum dots, respectively. The significant changes in the spectral features of all analytes have proven intercalative binding. The competitive study has confirmed that, daclatasvir, valacyclovir, and the quantum dots have exhibited groove binding. All analytes have shown good entropy and enthalpy values indicating stable interactions. 2023-04-21T02:54:20Z 2023-04-21T02:54:20Z 2023 Book https://link.springer.com/article/10.1186/s13065-023-00952-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/8189 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
sperm DNA of two antiviral agents |
| spellingShingle |
sperm DNA of two antiviral agents Ahmed Faried Abdel, Hakiem Ahmed Mohsen Kamal, El-Sagheir Mohammed E., Draz Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| description |
CC BY |
| format |
Book |
| author |
Ahmed Faried Abdel, Hakiem Ahmed Mohsen Kamal, El-Sagheir Mohammed E., Draz |
| author_facet |
Ahmed Faried Abdel, Hakiem Ahmed Mohsen Kamal, El-Sagheir Mohammed E., Draz |
| author_sort |
Ahmed Faried Abdel, Hakiem |
| title |
Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| title_short |
Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| title_full |
Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| title_fullStr |
Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| title_full_unstemmed |
Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| title_sort |
assessment of binding interaction to salmon sperm dna of two antiviral agents and ecofriendly nanoparticles comprehensive spectroscopic study |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s13065-023-00952-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/8189 |
| _version_ |
1763815058515689472 |
| score |
8.887836 |