Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate)
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
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Springer
2023
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| Truy cập trực tuyến: | https://link.springer.com/article/10.1186/s12934-023-02083-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8177 |
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oai:localhost:PNK-81772023-04-21T01:21:11Z Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) Hirotaka, Kudo Sho, Ono Kenta, Abe CoA CoaA CC BY Coenzyme A (CoA) is a carrier of acyl groups. This cofactor is synthesized from pantothenic acid in five steps. The phosphorylation of pantothenate is catalyzed by pantothenate kinase (CoaA), which is a key step in the CoA biosynthetic pathway. To determine whether the enhancement of the CoA biosynthetic pathway is effective for producing useful substances, the effect of elevated acetyl-CoA levels resulting from the introduction of the exogenous coaA gene on poly(3-hydroxybutyrate) [P(3HB)] synthesis was determined in Escherichia coli, which express the genes necessary for cyanobacterial polyhydroxyalkanoate synthesis (phaABEC). 2023-04-21T01:21:11Z 2023-04-21T01:21:11Z 2023 Book https://link.springer.com/article/10.1186/s12934-023-02083-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8177 en application/pdf Springer |
| institution |
Digital Phenikaa |
| collection |
Digital Phenikaa |
| language |
English |
| topic |
CoA CoaA |
| spellingShingle |
CoA CoaA Hirotaka, Kudo Sho, Ono Kenta, Abe Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| description |
CC BY |
| format |
Book |
| author |
Hirotaka, Kudo Sho, Ono Kenta, Abe |
| author_facet |
Hirotaka, Kudo Sho, Ono Kenta, Abe |
| author_sort |
Hirotaka, Kudo |
| title |
Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| title_short |
Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| title_full |
Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| title_fullStr |
Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| title_full_unstemmed |
Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| title_sort |
enhanced supply of acetyl-coa by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s12934-023-02083-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8177 |
| _version_ |
1763815057578262528 |
| score |
8.893527 |