Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers
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2023
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oai:localhost:PNK-81712023-04-20T09:04:08Z Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers Edip, Ajvazi Felix, Bauer Milan, Kracalik (meth)acrylate counterparts 3D printing of biomaterials CC BY Vinyl esters and carbonates have recently been demonstrated to have considerably lower cytotoxicity than their more commonly used (meth)acrylate counterparts, inspiring their use in the 3D printing of biomaterials. However, the degradation rates of such synthetic photopolymers are slow, especially in the mild conditions present in many biological environments. Some applications, for example, tissue regeneration scaffolds and drug release, require considerably faster biodegradation. Furthermore, it is essential to be able to easily tune the degradation rate to fit the requirements for a range of applications. Herein we present the design and synthesis of hydrolytically degradable polyphosphazenes substituted with a vinyl carbonate functionalized amino acid. Thiolene copolymerization with vinyl esters gave cured polymers which are demonstrated to considerably accelerate the degradation rates of cured vinylester/thiolene polymer scaffolds. 2023-04-20T09:04:08Z 2023-04-20T09:04:08Z 2023 Book https://link.springer.com/article/10.1007/s00706-023-03042-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/8171 en application/pdf Springer |
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(meth)acrylate counterparts 3D printing of biomaterials |
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(meth)acrylate counterparts 3D printing of biomaterials Edip, Ajvazi Felix, Bauer Milan, Kracalik Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
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CC BY |
format |
Book |
author |
Edip, Ajvazi Felix, Bauer Milan, Kracalik |
author_facet |
Edip, Ajvazi Felix, Bauer Milan, Kracalik |
author_sort |
Edip, Ajvazi |
title |
Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
title_short |
Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
title_full |
Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
title_fullStr |
Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
title_full_unstemmed |
Poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
title_sort |
poly[bis(serine ethyl ester)phosphazene] regulates the degradation rates of vinyl ester photopolymers |
publisher |
Springer |
publishDate |
2023 |
url |
https://link.springer.com/article/10.1007/s00706-023-03042-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/8171 |
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1763724456213086208 |
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8.891787 |