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Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method

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Bibliographic Details
Main Authors: Anna, Klimowska, Evelien, Wynendaele, Bartosz, Wielgomas
Format: Book
Language:Vietnamese
Published: Springer 2023
Subjects:
MSTFA
SPE-GC/MS/MS
Online Access:https://link.springer.com/article/10.1007/s00216-023-04633-7
https://dlib.phenikaa-uni.edu.vn/handle/PNK/8133
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spelling oai:localhost:PNK-81332023-04-20T04:41:24Z Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method Anna, Klimowska Evelien, Wynendaele Bartosz, Wielgomas MSTFA SPE-GC/MS/MS CC BY Nowadays, people are exposed to numerous man-made chemicals, many of which are ubiquitously present in our daily lives, and some of which can be hazardous to human health. Human biomonitoring plays an important role in exposure assessment, but complex exposure evaluation requires suitable tools. Therefore, routine analytical methods are needed to determine several biomarkers simultaneously. The aim of this study was to develop an analytical method for quantification and stability testing of 26 phenolic and acidic biomarkers of selected environmental pollutants (e.g., bisphenols, parabens, pesticide metabolites) in human urine. For this purpose, a solid-phase extraction coupled with gas chromatography and tandem mass spectrometry (SPE-GC/MS/MS) method was developed and validated. After enzymatic hydrolysis, urine samples were extracted using Bond Elut Plexa sorbent, and prior to GC, the analytes were derivatized with N-trimethylsilyl-N-methyl trifluoroacetamide (MSTFA). 2023-04-20T04:41:24Z 2023-04-20T04:41:24Z 2023 Book https://link.springer.com/article/10.1007/s00216-023-04633-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8133 vi application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language Vietnamese
topic MSTFA
SPE-GC/MS/MS
spellingShingle MSTFA
SPE-GC/MS/MS
Anna, Klimowska
Evelien, Wynendaele
Bartosz, Wielgomas
Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
description CC BY
format Book
author Anna, Klimowska
Evelien, Wynendaele
Bartosz, Wielgomas
author_facet Anna, Klimowska
Evelien, Wynendaele
Bartosz, Wielgomas
author_sort Anna, Klimowska
title Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
title_short Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
title_full Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
title_fullStr Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
title_full_unstemmed Quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the SPE-GC/MS/MS method
title_sort quantification and stability assessment of urinary phenolic and acidic biomarkers of non-persistent chemicals using the spe-gc/ms/ms method
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1007/s00216-023-04633-7
https://dlib.phenikaa-uni.edu.vn/handle/PNK/8133
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score 8.891145

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