Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements
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2023
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| Online Access: | https://link.springer.com/article/10.1186/s12938-023-01086-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/8091 |
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oai:localhost:PNK-80912023-04-19T07:42:11Z Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements Nikolai L., Bjørdalsbakke Jacob, Sturdy Emma M. L., Ingeström lumped parameter models longitudinal hemodynamic measurements CC BY Physics-based cardiovascular models are only recently being considered for disease diagnosis or prognosis in clinical settings. These models depend on parameters representing the physical and physiological properties of the modeled system. Personalizing these parameters may give insight into the specific state of the individual and etiology of disease. We applied a relatively fast model optimization scheme based on common local optimization methods to two model formulations of the left ventricle and systemic circulation. One closed-loop model and one open-loop model were applied. Intermittently collected hemodynamic data from an exercise motivation study were used to personalize these models for data from 25 participants. The hemodynamic data were collected for each participant at the start, middle and end of the trial. We constructed two data sets for the participants, both consisting of systolic and diastolic brachial pressure, stroke volume, and left-ventricular outflow tract velocity traces paired with either the finger arterial pressure waveform or the carotid pressure waveform. 2023-04-19T07:42:11Z 2023-04-19T07:42:11Z 2023 Book https://link.springer.com/article/10.1186/s12938-023-01086-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/8091 en application/pdf Springer |
| institution |
Digital Phenikaa |
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Digital Phenikaa |
| language |
English |
| topic |
lumped parameter models longitudinal hemodynamic measurements |
| spellingShingle |
lumped parameter models longitudinal hemodynamic measurements Nikolai L., Bjørdalsbakke Jacob, Sturdy Emma M. L., Ingeström Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| description |
CC BY |
| format |
Book |
| author |
Nikolai L., Bjørdalsbakke Jacob, Sturdy Emma M. L., Ingeström |
| author_facet |
Nikolai L., Bjørdalsbakke Jacob, Sturdy Emma M. L., Ingeström |
| author_sort |
Nikolai L., Bjørdalsbakke |
| title |
Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| title_short |
Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| title_full |
Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| title_fullStr |
Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| title_full_unstemmed |
Monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| title_sort |
monitoring variability in parameter estimates for lumped parameter models of the systemic circulation using longitudinal hemodynamic measurements |
| publisher |
Springer |
| publishDate |
2023 |
| url |
https://link.springer.com/article/10.1186/s12938-023-01086-y https://dlib.phenikaa-uni.edu.vn/handle/PNK/8091 |
| _version_ |
1763633857278509056 |
| score |
8.881002 |