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Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release

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Main Authors: Xiaowei, Mao, Kexin, Chen, Yanlong, Zhao
Format: Book
Language:English
Published: Springer 2023
Online Access:https://link.springer.com/article/10.1007/s40544-022-0648-z
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7948
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spelling oai:localhost:PNK-79482023-04-14T07:40:58Z Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release Xiaowei, Mao Kexin, Chen Yanlong, Zhao CC BY Osteoarthritis is associated with the significantly increased friction of the joint, which results in progressive and irreversible damage to the articular cartilage. A synergistic therapy integrating lubrication enhancement and drug delivery is recently proposed for the treatment of early-stage osteoarthritis. In the present study, bioinspired by the self-adhesion performance of mussels and super-lubrication property of articular cartilages, a biomimetic self-adhesive dopamine methacrylamide—poly(2-methacryloyloxyethyl phosphorylcholine) (DMA—MPC) copolymer was designed and synthesized via free radical polymerization. 2023-04-14T07:40:58Z 2023-04-14T07:40:58Z 2022 Book https://link.springer.com/article/10.1007/s40544-022-0648-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/7948 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
description CC BY
format Book
author Xiaowei, Mao
Kexin, Chen
Yanlong, Zhao
spellingShingle Xiaowei, Mao
Kexin, Chen
Yanlong, Zhao
Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
author_facet Xiaowei, Mao
Kexin, Chen
Yanlong, Zhao
author_sort Xiaowei, Mao
title Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
title_short Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
title_full Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
title_fullStr Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
title_full_unstemmed Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
title_sort bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1007/s40544-022-0648-z
https://dlib.phenikaa-uni.edu.vn/handle/PNK/7948
_version_ 1763180887516643328
score 8.881002

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