Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
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oai:localhost:PNK-69962023-03-20T08:35:42Z Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial Emil, Berta Josef, Srovnal Petr, Dytrych circulating tumor cells open colorectal cancer surgery CC BY Opioids and epidural analgesia are a mainstay of perioperative analgesia but their influence on cancer recurrence remains unclear. Based on retrospective data, we found that cancer recurrence following colorectal cancer surgery correlates with the number of circulating tumor cells (CTCs) in the early postoperative period. Also, morphine- but not piritramide-based postoperative analgesia increases the presence of CTCs and shortens cancer-specific survival. The influence of epidural analgesia on CTCs has not been studied yet. 2023-03-20T08:35:42Z 2023-03-20T08:35:42Z 2023 Book https://link.springer.com/article/10.1186/s12871-023-02007-1 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6996 en application/pdf Springer |
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circulating tumor cells open colorectal cancer surgery |
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circulating tumor cells open colorectal cancer surgery Emil, Berta Josef, Srovnal Petr, Dytrych Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial |
description |
CC BY |
format |
Book |
author |
Emil, Berta Josef, Srovnal Petr, Dytrych |
author_facet |
Emil, Berta Josef, Srovnal Petr, Dytrych |
author_sort |
Emil, Berta |
title |
Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial |
title_short |
Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial |
title_full |
Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial |
title_fullStr |
Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial |
title_full_unstemmed |
Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial |
title_sort |
influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (poacc-1): study protocol for a prospective randomized multicenter controlled trial |
publisher |
Springer |
publishDate |
2023 |
url |
https://link.springer.com/article/10.1186/s12871-023-02007-1 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6996 |
_version_ |
1760915946096033792 |
score |
8.889492 |