Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial

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Main Authors: Emil, Berta, Josef, Srovnal, Petr, Dytrych
Format: Book
Language:English
Published: Springer 2023
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Online Access:https://link.springer.com/article/10.1186/s12871-023-02007-1
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6996
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spelling oai:localhost:PNK-69962023-03-20T08:35:42Z Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial Emil, Berta Josef, Srovnal Petr, Dytrych circulating tumor cells open colorectal cancer surgery CC BY Opioids and epidural analgesia are a mainstay of perioperative analgesia but their influence on cancer recurrence remains unclear. Based on retrospective data, we found that cancer recurrence following colorectal cancer surgery correlates with the number of circulating tumor cells (CTCs) in the early postoperative period. Also, morphine- but not piritramide-based postoperative analgesia increases the presence of CTCs and shortens cancer-specific survival. The influence of epidural analgesia on CTCs has not been studied yet. 2023-03-20T08:35:42Z 2023-03-20T08:35:42Z 2023 Book https://link.springer.com/article/10.1186/s12871-023-02007-1 https://dlib.phenikaa-uni.edu.vn/handle/PNK/6996 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic circulating tumor cells
open colorectal cancer surgery
spellingShingle circulating tumor cells
open colorectal cancer surgery
Emil, Berta
Josef, Srovnal
Petr, Dytrych
Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
description CC BY
format Book
author Emil, Berta
Josef, Srovnal
Petr, Dytrych
author_facet Emil, Berta
Josef, Srovnal
Petr, Dytrych
author_sort Emil, Berta
title Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
title_short Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
title_full Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
title_fullStr Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
title_full_unstemmed Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial
title_sort influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (poacc-1): study protocol for a prospective randomized multicenter controlled trial
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1186/s12871-023-02007-1
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6996
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