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Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments

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Bibliographic Details
Main Authors: Yun, Li, Lina, Zhao, Qi, Zhou
Format: Book
Language:English
Published: Springer 2023
Subjects:
sleep deprivation
brain behavior and function
Online Access:https://link.springer.com/article/10.1007/s44254-023-00010-w
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6908
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spelling oai:localhost:PNK-69082023-03-16T04:56:10Z Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments Yun, Li Lina, Zhao Qi, Zhou sleep deprivation brain behavior and function CC BY Sleep plays an important role in people's physical and mental health [1]. Good sleep can not only effectively enhance the brain's ability to remove harmful substances, but also help maintain brain function [2], including mental health, supporting learning and memory, and regulating synaptic plasticity, in the process of which genes involved in sleep, especially those expressions with the circadian rhythm in brain, are crucial regulators [3]. Recent research evidence has shown circadian regulation of sleep-dependent gene expression produces short-term or even long-term changes in brain behavior and function [4]. Conversely, sleep deprivation (SD) may damage the brain by disrupting gene expression related to the sleep–wake cycle of synaptic proteins [3, 5]. SD can affect gene expression, especially those involved in neuronal plasticity and neuropsychiatric disorders, which are critical for brain health [3, 6]. 2023-03-16T04:17:33Z 2023-03-16T04:17:33Z 2023 Book https://link.springer.com/article/10.1007/s44254-023-00010-w https://dlib.phenikaa-uni.edu.vn/handle/PNK/6908 en application/pdf Springer
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic sleep deprivation
brain behavior and function
spellingShingle sleep deprivation
brain behavior and function
Yun, Li
Lina, Zhao
Qi, Zhou
Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
description CC BY
format Book
author Yun, Li
Lina, Zhao
Qi, Zhou
author_facet Yun, Li
Lina, Zhao
Qi, Zhou
author_sort Yun, Li
title Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
title_short Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
title_full Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
title_fullStr Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
title_full_unstemmed Analysis of sleep deprivation-associated Homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
title_sort analysis of sleep deprivation-associated homer1 gene and protein acting on synaptic plasticity by bioinformatics and animal experiments
publisher Springer
publishDate 2023
url https://link.springer.com/article/10.1007/s44254-023-00010-w
https://dlib.phenikaa-uni.edu.vn/handle/PNK/6908
_version_ 1760553558114041856
score 8.881002

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