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Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening

Distichochlamys citrea is an endemic plant species found only in Vietnam, known by folk medicine as a natural antibiotic source. Experimental evidences and computational validation on bioactivity of Distichochlamys citrea M.F. Newman rhizome n-hexane extract against Streptococcus pyogenes were carri...

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Main Authors: Dr. Nguyen Van Hue, Dr. To Dao Cuong, Dr. Phan Tu Quy
Format: Bài trích
Language:English
Published: John Wiley & Sons 2022
Subjects:
Distichochlamys citrea
Rhizome n -Hexane
Online Access:https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202200680
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5976
https://doi.org/10.1002/slct.202200680
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spelling oai:localhost:PNK-59762022-08-17T05:54:51Z Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening Dr. Nguyen Van Hue Dr. To Dao Cuong Dr. Phan Tu Quy Distichochlamys citrea Rhizome n -Hexane Distichochlamys citrea is an endemic plant species found only in Vietnam, known by folk medicine as a natural antibiotic source. Experimental evidences and computational validation on bioactivity of Distichochlamys citrea M.F. Newman rhizome n-hexane extract against Streptococcus pyogenes were carried out. Experiments found twenty-one bioactive components in the n-hexane extract, which altogether exhibits an overall antibiotic activity of significance against the bacterium; Computations suggested a mechanism based on inhibition of S-ribosylhomocysteine lyase structure. Its biocompatibility and pharmacology were also predicted. 2022-07-13T02:00:12Z 2022-07-13T02:00:12Z 2022 Bài trích https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202200680 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5976 https://doi.org/10.1002/slct.202200680 en John Wiley & Sons
institution Digital Phenikaa
collection Digital Phenikaa
language English
topic Distichochlamys citrea
Rhizome n -Hexane
spellingShingle Distichochlamys citrea
Rhizome n -Hexane
Dr. Nguyen Van Hue
Dr. To Dao Cuong
Dr. Phan Tu Quy
Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
description Distichochlamys citrea is an endemic plant species found only in Vietnam, known by folk medicine as a natural antibiotic source. Experimental evidences and computational validation on bioactivity of Distichochlamys citrea M.F. Newman rhizome n-hexane extract against Streptococcus pyogenes were carried out. Experiments found twenty-one bioactive components in the n-hexane extract, which altogether exhibits an overall antibiotic activity of significance against the bacterium; Computations suggested a mechanism based on inhibition of S-ribosylhomocysteine lyase structure. Its biocompatibility and pharmacology were also predicted.
format Bài trích
author Dr. Nguyen Van Hue
Dr. To Dao Cuong
Dr. Phan Tu Quy
author_facet Dr. Nguyen Van Hue
Dr. To Dao Cuong
Dr. Phan Tu Quy
author_sort Dr. Nguyen Van Hue
title Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
title_short Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
title_full Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
title_fullStr Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
title_full_unstemmed Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
title_sort antimicrobial properties of distichochlamys citrea m.f. newman rhizome n -hexane extract against streptococcus pyogenes : experimental evidences and computational screening
publisher John Wiley & Sons
publishDate 2022
url https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202200680
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5976
https://doi.org/10.1002/slct.202200680
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score 8.891145

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