Design, synthesis and evaluation of novel 2-oxoindoline-based acetohydrazides as antitumor agents
In our search for novel small molecules activating procaspase-3, we have designed and synthesized two series of novel (E)-N'-arylidene-2-(2-oxoindolin-1-yl)acetohydrazides (4) and (Z)-2-(5-substituted-2-oxoindolin-1-yl)-N'-(2-oxoindolin-3-ylidene)acetohydrazides (5). Cytotoxic evaluation r...
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| Main Authors: | , , , |
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| Format: | Bài trích |
| Language: | English |
| Published: |
Springer
2022
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| Subjects: | |
| Online Access: | https://www.nature.com/articles/s41598-022-06887-0 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5879 https://doi.org/10.1038/s41598-022-06887-0 |
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