Adenovirus-α-Defensin Complexes Induce NLRP3-Associated Maturation of Human Phagocytes via Toll-Like Receptor 4 Engagement
Intramuscular delivery of human adenovirus (HAdV)-based vaccines leads to rapid recruitment of neutrophils, which then release antimicrobial peptides/proteins (AMPs). How these AMPs influence vaccine efficacy over the subsequent 24 h is poorly understood. In this study, we asked if human neutrophil...
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Main Authors: | Karsten, Eichholz, Tuan Hiep, Tran, Coraline, Chéneau, Thi Thu Phuong, Tran, Océane, Paris |
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Format: | Bài trích |
Language: | English |
Published: |
American Society for Microbiology
2022
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Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/jvi.01850-21 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5875 https://doi.org/10.1128/jvi.01850-21 |
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