Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3-yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents
A biological evaluation revealed that all thirteen compounds designed and synthesized showed strong cytotoxicity against three human cancer cell lines (SW620, colon cancer; PC-3, prostate cancer; NCI-H23, lung cancer) with eight compounds (5a, 5c-i, 5k), which were clearly more potent than both PAC-...
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| Main Authors: | , , |
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| Format: | Bài trích |
| Language: | English |
| Published: |
Bentham Science Publishers
2022
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| Subjects: | |
| Online Access: | https://www.eurekaselect.com/article/120263 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5864 https://doi.org/10.2174/1871520622666220118154914 |
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