Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons
A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy de...
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Wiley & Sons
2022
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oai:localhost:PNK-57232022-08-17T05:54:50Z Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons Anh, D. Phan Nguyen, K. Ngan Do, T. Nga Nam, B. Le Chu, Viet Ha Medical Physics IET Nanobiotechnology A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy depends on optical properties of graphene plasmons, which are sensitive to structural parameters, and concentration of plasmonic nanostructures. By using theoretical modelling, temperature gradients of the bulk drug with different concentrations of graphene plasmons are calculated. From these, the temperature dependence of structural molecular relaxation and diffusion of indomethacin are determined and how the heating process significantly enhances the drug mobility is found out 2022-05-05T07:26:12Z 2022-05-05T07:26:12Z 2022 Bài trích https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5723 https://doi.org/10.1002/pssr.202100496 en Wiley & Sons |
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Medical Physics IET Nanobiotechnology |
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Medical Physics IET Nanobiotechnology Anh, D. Phan Nguyen, K. Ngan Do, T. Nga Nam, B. Le Chu, Viet Ha Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
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A theoretical approach to quantitatively determine the photothermally driven enhancement of molecular mobility of graphene-indomethacin mixtures under infrared laser irradiation is proposed. Graphene plasmons absorb incident electromagnetic energy and dissipate them into heat. The absorbed energy depends on optical properties of graphene plasmons, which are sensitive to structural parameters, and concentration of plasmonic nanostructures. By using theoretical modelling, temperature gradients of the bulk drug with different concentrations of graphene plasmons are calculated. From these, the temperature dependence of structural molecular relaxation and diffusion of indomethacin are determined and how the heating process significantly enhances the drug mobility is found out |
format |
Bài trích |
author |
Anh, D. Phan Nguyen, K. Ngan Do, T. Nga Nam, B. Le Chu, Viet Ha |
author_facet |
Anh, D. Phan Nguyen, K. Ngan Do, T. Nga Nam, B. Le Chu, Viet Ha |
author_sort |
Anh, D. Phan |
title |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_short |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_full |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_fullStr |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_full_unstemmed |
Tailoring Drug Mobility by Photothermal Heating of Graphene Plasmons |
title_sort |
tailoring drug mobility by photothermal heating of graphene plasmons |
publisher |
Wiley & Sons |
publishDate |
2022 |
url |
https://onlinelibrary.wiley.com/doi/10.1002/pssr.202100496 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5723 https://doi.org/10.1002/pssr.202100496 |
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1751856279542824960 |
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8.891053 |